Potentiation of glutathione loss and nerve cell death by the transition metals iron and copper: Implications for age related neurodegenerative diseases ScienceDirect Brain health depends on balance. From energy production to antioxidant protection and immune regulation, multiple systems work together to support how the brain functions. Glutathione plays a central role in maintaining Brain health depends on balance. From energy production to antioxidant protection and immune regulation, multiple systems work together to support how the brain functions. Glutathione plays a central role in maintaining Glutathione